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developed to overcome all-trans retinoic acid (ATRA) resistance
CAS Number: 802906-73-6
KN-93 phosphate
Berberine inhibits the growth of human colorectal adenocarcinoma in vitro and in vivo
Bafetinib analog, Lyn-IN-1 - CAS# 887650-05-7 clozanide developed to overcome all-trans retinoicBafetinib, also known as INNO 406 and NS187, is an orally bioavailable 2 phenylaminopyrimidine derivative with potential antineoplastic activity. Bafetinib specifically binds to and inhibits the Bcr Abl fusion protein tyrosine kinase, an abnormal enzyme produced by Philadelphia chromosomal translocation associated with chronic myeloid leukemia (CML). This agent also inhibits the Src family member Lyn tyrosine kinase, upregulated in imatinib resistant
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